'Do We Want to Know?' Psychoanalyst Exposes Weak Evidence and Urges Exploration Before Medicalization
Do we want to know?
- Authors
- D'Angelo, R.
- Year
- 2025
- Journal
- The International Journal of Psychoanalysis
Methodological Limitations
- Single case study. The paper relies primarily on one detailed clinical case (Elly), which limits generalisability. No broader sample or comparative data is presented.
- Anonymised and unverifiable. Patient details are altered for confidentiality, making independent verification of the clinical account impossible.
- No control or comparison group. There is no discussion of cases where affirmation or medical transition led to positive outcomes, creating an asymmetrical presentation.
- Author's declared conflict of interest. D'Angelo is President of the Society for Evidence-Based Gender Medicine (SEGM), an organisation critical of affirmative care, which may influence framing and interpretation.
- Selective literature review. The paper heavily cites systematic reviews critical of youth gender medicine while not engaging with research supporting affirmative outcomes, potentially skewing the evidence picture.
- Interpretive reliance on countertransference. Core clinical insights derive from the analyst's subjective experience and theoretical framework, which are not independently confirmable.
- Retrospective reconstruction. Elly's traumatic history and its link to gender identity emerged over time and are reconstructed narratively; causal direction remains speculative.
- Potential sampling bias. The patient population (trans-identified youth in psychoanalytic treatment seeking or referred for exploration) may not represent the broader clinical population.
- Limited engagement with opposing analytic perspectives. While critiquing colleagues at length, the paper does not systematically address their clinical data or case material on its own terms.
- Socio-political context as confound. The author acknowledges that the contemporary climate shapes both patient and analyst behaviour, yet does not fully account for how his own positioning within that polarised debate may influence clinical perception and reporting.
Key Findings
- Trauma can hide behind a fixed trans narrative. In the case of Elly, a history of maternal abuse and emotional neglect only emerged after 18 months of analytic work, revealing her gender dysphoria was deeply entangled with unprocessed psychic pain that brief clinic assessments would never have uncovered.
- The medical evidence base is shaky. Systematic reviews from the UK (Cass Review), Sweden, Finland and Germany consistently find that evidence for the benefits of puberty blockers and cross-sex hormones in youth is of very low quality, while serious physical harms—including cardiovascular risks and infertility—are well established.
- There is a "prohibition on knowing" at every level. Patients like Elly fiercely defend against exploration of their gendered experience, and this individual resistance is reinforced by a socio-political climate that frames any questioning of trans identity as transphobic or a form of conversion therapy.
- Advocacy within psychoanalysis is misrepresenting exploratory work. Prominent analysts who promote medical affirmation are, in D'Angelo's view, distorting the intent of clinicians who ask "why," erasing the suffering of detransitioners, and abandoning the analytic mandate to understand unconscious meaning.
- The profession may be over-correcting for its past. The analytic community's defensive rush to affirm medical transition may be driven by unconscious guilt over its history of pathologising homosexuality, coupled with clinicians avoiding the dread and helplessness that arise when sitting with a young person pursuing irreversible body modification.
Abstract
The weak evidence base and profound consequences of gender- affirming interventions for youth call for a particularly sensitive and complex psychoanalytic exploration. However, prohibitions on knowing at the individual and social levels significantly constrain psychoanalytic work with trans-identified youth. Barriers to exploration and thinking that patients bring to treatment are reinforced and reified by the dominant socio-political trends that saturate the contexts in which young people dwell. These trends increasingly frame any attempt to deeply explore why a young person is seeking medical or surgical gender-affirming interventions as “off-limits” and a form of conversion therapy. Furthermore, politically driven clinicians who promote medical gender-affirming interventions misrepresent and attempt to discredit clinicians who explore the meaning and function of trans identification, or who express concern that transitioning may be a drastic solution to various forms of psychic pain. In doing so, they minimise the significance of the weak evidence base for these interventions and their serious, known risks. At the same time, they obscure or deny the psychic pain that is sometimes humming beneath the experience of gender dysphoria. The author asks: If there are significant uncertainties and risks of harm associated with medical interventions for young people, do we want to know?
Summary
Roberto D'Angelo's paper argues that psychoanalytic exploration with gender-dysphoric youth is being blocked by powerful "prohibitions on knowing" that operate within patients, the consulting room, and broader socio-political discourse. Through the case of "Elly"—a trans-identified adolescent whose fixed narrative of being "born in the wrong body" eventually gave way to traumatic memories of maternal abuse and a fantasy that being female would have meant being loved—D'Angelo demonstrates how prolonged analytic work can reveal that gender dysphoria sometimes carries deeper psychic pain invisible in brief clinic assessments. He critiques the weak evidence base for youth gender-affirming medicine, citing systematic reviews from the UK's Cass Review, Sweden, Finland and Germany that found benefits uncertain while harms (cardiovascular risks, infertility, irreversible changes) are established. Given this, he contends thorough psychological exploration is ethically mandatory before irreversible treatment—not "gatekeeping" or "conversion therapy." D'Angelo sharply criticises fellow analysts who frame exploratory work as transphobic or "eugenicist," arguing they misrepresent colleagues' intent, erase detransitioners' suffering, and foreclose the analytic mandate to understand unconscious meaning. He suggests the analytic community's defensive rush to affirm may stem from unconscious guilt over its history of pathologising homosexuality, plus countertransference avoidance—affirmation spares clinicians the dread of sitting with a young person pursuing irreversible body modification. He concludes that psychoanalysis must resist these pressures and ask: if serious harms are possible, do we want to know?
Conclusion
D'Angelo concludes that psychoanalysis has an ethical duty to resist these prohibitions. The analytic process—slow, uncertain, and often uncomfortable—is precisely what can help young people determine whether transition will help them thrive or whether their gender dysphoria is a carrier for other, unaddressed pain. He asks the profession directly: if there are serious uncertainties and risks of harm, do we want to know?