Key Findings

• 93% of adolescents continued GAH
• Only 0.5% reidentified with birth sex
• 1,050 patients at Boston Children's Hospital
• Discontinuation associated with identity change, pregnancy desire, side effects
• Low discontinuation rate suggests treatment satisfaction

Abstract

Retrospective cohort study of 1,050 transgender adolescents at Boston Children's Hospital examining GAH discontinuation rates and reasons.

Summary

This study found very low rates of GAH discontinuation among transgender adolescents, with most continuing treatment. The findings suggest that discontinuation is rare and typically driven by specific life changes rather than regret.

Conclusion

GAH discontinuation is rare among transgender adolescents, with most continuing treatment. When discontinuation occurs, it is typically due to change in gender identity, desire for pregnancy, or side effects.